Endocrine Abstracts

Background: Diabetes is characterized by a prolonged latency between the onset of metabolic abnormalities and the clinical appearance of microvascular disease, consistent with the occurrence of vascular repair in the early stages. Patrolling monocytes (PMo), a subset of circulating monocytes, survey microvessels by crawling on the endothelium; their functional and biosynthetic characteristics suggest they play a role in the protection of the endothelium from vascular stress.</...